Mac OS X has never been the best platform for SEO software, and although Bootcamp, Parallels and VMware Fusion have provided a way to use Windows based SEO software on a Mac, I still personally prefer to work in Mac OS X where possible.
Here are some Mac SEO applications I have discovered -
Advanced Web Ranking allows you to check your websites ranking in a wide range of search engines for specified keyword phrases and compare how it’s performing to your competitors. Reports can be saved which is useful to monitor changes over time. Advanced Web Ranking comes in three versions - Standard, Professional and Enterprise, and a fully featured trial can be downloaded for free.
Rank Tracker also allows you to check your websites ranking but in a more limited number of search engines, and it only shows your sites ranking - not your competitors. One notable feature though is the integration of keyword suggestion tools. Rank Tracker can be used for free though if you need to save projects you will need to upgrade to a Professional license.
Google Sitemap Automator - as the name suggests this application automates the process of creating Google site maps, which can then be used to help Google crawl your website more effectively.
iSEO - enter a web address into this handy little widget and it quickly returns various useful information about a site including page rank, alexa ranking, and number of backward links.
I am always on the lookout for more Mac SEO software, please feel free to share links.